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The fundamental aim of this Call is to foster groundbreaking and highly relevant research projects that lead to the advancement of knowledge and offer solutions related to some of the most significant health problems of our century. The ¿la Caixa¿ Foundation seeks research projects of scientific excellence in their field, with great potential value and a high social impact. The "la Caixa" Foundation encourages applicants to present projects with an innovative focus that transcend the boundaries between different areas of research, aimed at new and emerging research fields and/or including unconventional approaches to health problems.

Projects eligible for this call must be led by non-profit Research Performing Organizations (Host Organizations) based in Spain or Portugal.

The Projects must be submitted in one of the following five Thematic Areas:
· Neuroscience.
· Infectious diseases.
· Oncology.
· Cardiovascular and associated metabolic diseases:projects in cardiovascular diseases and metabolic diseases associated with cardiovascular risks or alterations.
· Enabling technologies:projects focused on the creation and development of health-facilitating technologies coming from fields such as micro and nanoelectronics, computational science, big data, photonics, nanotechnology, biotechnology, advanced materials or advanced manufacturing, among others. Projects should also be focused to address topics of the four previous thematic areas.

The Projects shall have a duration of up to 3 years and may be submitted as Individual or Research Consortium projects.
· Individual projects are submitted by a sole Research Performing Organization (RPO) i.e. the Host Insitution.
· Research Consortium projects are submitted by a Research Consortium (composed by a minimum of 2 and a maximum of 5 RPOs, including the Host Organization).

The Projects will be coordinated by the Host Organization. Additionally, both Individual and Research Consortium projects may also include Civil Society Organizations, non-research perfoming civil society organizations that carry out activities of the Project). A maximum of three Civil Society Organizations are permitted per proposal.

The Call aims to support basic, clinical and translational research projects.

The fact that the Proposals are submitted as Individual or Research Consortium projects, and classified as Basic, Clinical or Translational will not in any case be a selection criterion during the evaluation process.

Grants may be awarded up to €19,000,000* to support the selected Projects. The intention is to distribute this amount approximately equitably amongst the different Thematic Areas, but the final distribution will always depend on the quality and the specific characteristics of the Projects submitted to this Call.
* This amount is subject to final approval by ¿la Caixa¿ Foundation.
The Francisco Luzón Foundation will co-fund one project on Amyotrophic Lateral Sclerosis (ALS).
"la Caixa" Foundation and the Fundação para a Ciência e a Tecnologia (FCT) collaborate by means of the Iniciativa Ibérica de Investigação e Inovação Biomédica (i4B) within the framework of the Call. Under this initiative, the FCT may fund additional projects among the best ranked proposals with a Portuguese component.

Funding

The economic amount of the grants for the Projects is detailed below:
· Individual Projects can request a grant up to €500,000.
· Research Consortium Projects can request a grant up to €1,000,000.

The grant will be awarded to the Host Organization, which will be responsible for distributing the budget to the other Organizations.

When preparing the budget, the following criteria and requirements must be taken into account:
a) Projects that request a grant of more than €500,000 must include in their budget the cost of an external audit to be carried out by the Host Organization at the end of the duration of the Project.
b) Both Research Performing Organizations and Civil Society Organizations must carry out activities of the Project to be part of the Consortium. All Research Performing Organizations must have an allocated budget. Having an allocated budget is not mandatory for Civil Society Organizations, however their partipation in the proposal has to be justified.
c) For-profit entities (including companies) cannot be partners of consortiums. This type of entities can only receive Project funds if they are subcontracted by a Research Performing Organization.
d) The sum of the budgets of all the Research Performing Organizations and the Civil Society Organizations not located in Spain or Portugal cannot exceed the 30% of the total budget of the Project.

The grant will cover the costs related to the Project as long as they are adequately justified, technically adapted to the needs of the project and always in accordance with the policies of the Organization. The Proposal budget may include expenses in the following concepts:

a) Direct costs:
/ Personnel
/ Travel
/ Equipment
/ Consumables
/ Publications
/ Dissemination and social engagement activities
/ Other direct costs

b) Indirect costs (overheads):a maximum of 10% per Organization of the direct costs of the budget of the grant:Indirect costsmax = 0.1 x Direct Costs

c) Subcontracting
/ Subcontracting audits
/ Others subcontracting

Eligibility criteria

The Host Organization must be a Research Performing Organization (a non-profit organization dedicated to research in accordance with the definition of section 0) based in Spain or Portugal.

People who act as Project Leader (PL) and PI must be of legal age and may be of any nationality. The PL must have a minimum of 7 years of experience in postdoctoral research. 

Within the same Call, each PL can only submit a single proposal as a PL;however, they can collaborate on other Projects as PI of a RPO of the Research Consortium or as a Team Member.

The PLs of Projects awarded with a grant from the CaixaResearch Health Call will not be allowed to submit a new Proposal as PL in the three subsequent editions of the call.

The PL and the PIs of a proposal that obtained a score of less than 5.50 in the remote evaluation phase of the previous edition of the Call (CaixaResearch Health Call 2021) are not allowed to submit proposals as PLs to this edition of the Call (2022).

The Application must be submitted electronically through the la Caixa Foundation's online system.

The whole process of submission and selection of Applications, including the interview, will be carried out in English. All information must be submitted in English.

Proposals will be evaluated based on the Thematic Area selected in the Application. The following information will also need to be provided for the best assignment of the evaluators to each project:
· Basic/Clinical/Translational nature of the project (up to two options may be selected)
· Keywords:a minimum of 1 and a maximum of 3 main keywords for the best description of the Project. A minimum of 3 and a maximum of 5 other important keywords will complete the description of your proposal.

The online system will be open for Applications from September 28, 2020 at 14:00h Central European Time (CET) until November 25, 2021 at 14:00h, CET.


Protecció de dades de caràcter personal
Les dades facilitades seran incorporades en el fitxer de dades de caràcter personal "Gestió de la recerca", titularitat de la Universitat Pompeu Fabra amb la finalitat de gestionar els ajuts i els convenis de R+D+I. Aquestes dades només podran ser cedides quan sigui necessari per a desenvolupar una relació jurídica amb la persona interessada (organismes públics per a la tramitació i justificació d'ajuts oficials), i en aquells casos en què sigui necessari per al compliment de les obligacions legalment establertes. En qualsevol moment podeu exercir els drets d'accés, rectificació, cancel•lació i oposició mitjançant comunicació escrita, acompanyada d'una fotocòpia del DNI o document equivalent adreçada a: Gerent. Universitat Pompeu Fabra. Pl. de la Mercè, 10-12. 08002 Barcelona